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Can effects target a destroyed building, and what happens if one is named?

A destroyed building is off the board, so area or adjacent-building effects skip it and do nothing when no building remains (like the Frost Troll's 'on or adjacent' skulls). An effect that names one specific building that is already destroyed, such as the citadel, cannot be resolved, so its skulls are removed and the resolving player takes a corruption.

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