Pandemic: The Cure
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Can you spend + dice to re-roll Hot Zone dice on turns other than the one they were spent?
The designer confirmed the two rules are separate, with future-turn re-rolls allowed.
- Tom Lehmann · Designer · 2017-02-16
On a later turn, during Do Actions, you may spend a + die to re-roll the hot zone dice in the current player's region. A Hazardous Sample die spent during Try to Find a Cure cannot be re-rolled straight away, because that happens outside Do Actions.