Keep the Heroes Out!
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What wakes an exhausted hero?
The designer confirmed this on BGG repeatedly, and it follows the rulebook's Inspire step.
Only another hero. An active hero that moves into the room, or is summoned there, inspires the exhausted heroes already in it. A hero type that runs out reactivates all of its type, and some scenario cards also reactivate heroes. A monster entering the room does not wake a hero, and heroes already in the vault can be inspired by a hero moving in.